Back-up(s) to the terrabyte device and the new 32gig flash drive ($20 at Best Buy, like whoa).
Cleaned out system files.
Deleted all offending temp files. Prayed at the altar of registries. Nortoncized, full disk scan (>1 hour).
Getting ready to call in the Big Guns in India.
Having fun on the computer ... no one said, ever.